Hi, I have also been on effexor for aprox 2-3 years now. I went through a terrible, depressing pregnancy, and an even worse post-partum depression until my doc put me on effexor. I was always fairly thin and able to control my weight, fast forward to now, doesn't seem to matter what I do, my weight just keeps increasing and am now heavier than when I was pregnant! I also have experienced the low low low libido.....both of these side effects my doc, at the time, told me is not a symptom....bologne! I think the main issue that we all seem to be having is our doctors are all saying different things, which makes it difficult to know what to do. I don't have an answer, but wanted to let you know you are not alone!