Hi there,
From the searching I have done on-line it seems as though everyone has heard/done different things so I am going to share what I have been told by my OB and phych and you can take what you'd like from it.
I was on 60mg of Cymbalta for about 2 years when I found out I was pregnant. When I saw my OB on my initial visit (I was 5 weeks) she suggested that I see my phych and come off of the medication if at all possible. I weaned off quickly (30 mg a day for 1 week) and although I did have some side effects I didn't thik it was as bad as it could have been given my prolonged use. I have felt pretty good since, my OB believes that the hormones produced during pregnancy help balence things out without the Cymbalta.
My OB has me seeing a specialist for additional ultrasounds and a couple of eco-cardiograms for monitoring as she has read that Cymbalta and related medications can cause heart defects and abnormalities in the development of the baby's internal organs, spcifically the stomach. Being that much of this development takes place in the early weeks of pregnancy she stated that I should come off of the Cymbalta ass soon as possible (I was off by 9 weeks) and if NEEDED I could go back on the medication for the 2nd trimester, and wean off again for the 3rd to get the medication out of the baby's system before birth.
I don't feel that I need to go back on thankfully and I think that if I did feel the need I would be reluctant both for the baby's safety and because I don't want to go thru the withdrawal again.
Good luck to everyone and please get the advice of your OB and phych before doing anything.
Deb