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Weekly Check-Up: Identical Twins Not So Identical

Posted by Kelly Mills

good and evil twins? Until relatively recently, scientists believed identical twins were completely identical right on down to the DNA level. But this left some puzzles: Why, for example, would one twin develop a disease like Parkinson's while the other did not? It seemed odd that this could be explained by environmental exposures alone. And on a totally anecdotal and unscientific level, I've known identical twins with different personalities, and it also seems unlikely that those variations could be explained entirely by subtle differences in the way the twins were treated in the same family. 

Now researchers have found possible DNA factors that complicate the picture and offer some reasons for differences among twins. When humans receive chromosones, sometimes there are pieces of DNA missing, or mutations cause a few copies of the same piece of DNA. This is called copy number variation (CNV) and in a study of identical twins, researchers found differences in CNV between sets of twins. Now maybe this will explain how a good person can have an identical evil twin... Mwah ha ha.

Anyone notice differences in their twins?    


Comments

 

wendy said:

ummm...I think Ashley and Mary-Kate are fraternal twins.......

February 21, 2008 10:49 AM
 

Kelly Mills said:

Ooops. Yes, a li'l googlin' confirms that. Clearly I need to do a better job of being up on the lives of Mary Kate and Ashley. One site says they both like pink--see, I'm learning!

February 21, 2008 11:29 AM
 

Janice said:

I don't have twins but my stepmother has an identical twin.  The sister has schizophrenia, but my stepmother doesn't.  Apparently it is pretty rare for only one to have it, they were involved in studies years ago.

February 21, 2008 11:55 AM
 

HDCS said:

Epigenetics are teh new hotness. The genome projects are just the tip of the iceberg when it comes to understanding genetics. Fundamentally research is finding that environmental factors can and do impact genetics, and things like this are a key indicator of that. So knowing our genes and what they mean is only a small part of the puzzle.

Watch Nova and Nova Science Now. Some really good stuff there.

February 21, 2008 12:36 PM
 

Kelly Mills said:

Ooops. Yes, a li'l googlin' confirms that. Clearly I need to do a better job of being up on the lives of Mary Kate and Ashley. One site says they both like pink--see, I'm learning!

February 21, 2008 1:04 PM

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