When I was trying my damndest to get knocked up and it wasn't happening, I got to go see the fertility specialist. I sat down and we reviewed my charts and my tests and my not-being-pregnant-ness, and he make murmuring sounds. Then he put down his pen and looked me straight in the eyes and said, "You may need to go straight to IVF." "Wha?" I stammered. "Well, when we don't know what's wrong, sometimes the easiest way is just to do IVF," he replied. Turns out he was just ahead of the curve.
Slate has a bit on how IVF is the surest and quickest way sometimes for the infertile to conceive. For a while it has been considered a last resort, but folks are arguing that some of the other methods turn out to waste months--and for older infertile moms, months make a difference. IVF also doesn't result in the same incidence of multiples as other methods, which is huge. There's also the issue of money, in that you can spend lots of cash trying less invasive procedures and ultimately end up forking over the big IVF dollars anyway. However, it's a hard call, because IVF is not cheap, and I, for example, live in a state that doesn't require insurance companies to cover it. And while we are on the subject, I'd like to say that I think the lack of infertility insurance coverage is wholly messed up, and basically means only people who have bucks or can do a second mortgage even get to try out IVF. Which is, in my professional opinion, crappy.